To date, only trivalent influenza vaccines have been used in the Russian Federation. In 2019, the Ministry of
Health, together with Rospotrebnadzor, developed and approved a Phased Transition Plan for the use of quadrivalent
vaccines to prevent influenza as part of the National Preventive Vaccination Calendar between 2019 and 2021.
Grippol®Quadrivalent contains 4 of the most common antigenic strains, which means that once it is administered and
an immune response is formed, a person has a broader spectrum of protection against different types of viruses.
Accordingly, the risk of contracting influenza is reduced.
4-valent influenza vaccines have greater prophylactic and pharmacoeconomic efficacy than 3-valent vaccines
In Russia, a switch from the 3-valent to the 4-valent vaccine could prevent up to 265,8 thousand
cases of influenza per season3